Medical Researches
Moderately Effective
Based on 10 Researches
Lacticaseibacillus rhamnosus shows promiseIn Vitro and In Vivo Evaluation of Lacticaseibacillus rhamnosus GG and Bifidobacterium lactis Bb12 Against Avian Pathogenic Escherichia coli and Identification of Novel Probiotic-Derived Bioactive Peptides.
High relevance for poultry health
We explored the potential of Lacticaseibacillus rhamnosus GG as a probiotic treatment against avian pathogenic E. coli (APEC) in chickens. Our study showed that this probiotic significantly reduced APEC colonization in the chickens' cecum and improved the balance of gut microbiota over a 24-hour period.
Through laboratory evaluations, we detected novel bioactive peptides in the probiotic's culture supernatants, which may contribute to its antibacterial properties. While the results are promising for poultry health, more research is needed to optimize its use in real farming conditions.
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We explored the effectiveness of a synbiotic treatment combining Bifidobacterium longum and xylo-oligosaccharides in fighting Campylobacter jejuni, a major cause of food poisoning. The treatment was administered either from day one or day fourteen of the chicks' lives.
Our findings showed that early supplementation led to a significant reduction in C. jejuni levels compared to later treatment. However, Bifidobacterium levels did not significantly differ among treatment groups. These results suggest that early synbiotic use alongside other safety measures could help improve poultry meat safety.
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We aimed to see how a synbiotic mixture might help reduce Campylobacter jejuni, a harmful bacteria often found in poultry, which can cause food poisoning in humans. Through our research, we provided broiler chickens with a blend of prebiotics and a specific strain of Bifidobacterium longum.
After 14 days, we observed a significant reduction in C. jejuni levels in the feces of treated chickens. This suggests that such synbiotic treatments could be an effective strategy for enhancing poultry safety and reducing foodborne illnesses linked to poultry products.
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We explored the effectiveness of two probiotic strains, specifically Lactobacillus plantarum PCS 20 and Bifidobacterium longum PCB 133, in reducing Campylobacter jejuni in poultry. After thorough screening of 55 bacteria for their ability to combat this common pathogen, B. longum was found to thrive in the chickens' digestive systems after two weeks, while L. plantarum was undetectable. Most importantly, B. longum significantly lowered C. jejuni levels in feces, suggesting its potential as a feed additive to improve food safety.
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Lactococcus lactis enhances toxin immunityOral immunization of mice with Lactococcus lactis expressing Shiga toxin truncate confers enhanced protection against Shiga toxins of Escherichia coli O157:H7 and Shigella dysenteriae.
Study relevant for vaccine development
We explored the potential of Lactococcus lactis (L. lactis) as an oral vaccine to fight against harmful Shiga toxins produced by bacteria such as E. coli O157:H7 and Shigella dysenteriae. In our study with BALB/c mice, those immunized with a specific strain of L. lactis showed impressive protection, with survival rates of 84% and 100% when exposed to these toxins. The immunization resulted in significant antibody production and minimized organ damage, demonstrating L. lactis's promising role in developing an effective oral vaccine against these toxins.
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User Reviews
I have always had stomach problems, particularly after eating spicy or oily foods which led to food poisoning. Since taking this probiotic daily for around six months, my stomach issues have greatly subsided.
Excellent probiotics! After a strong course of antibiotics, my stomach, duodenum, and intestines became inflamed, causing severe pain from any food. By taking these probiotics—four drops daily with meals—I experienced relief within days. I recommend a course lasting at least one month alongside enzymes and l-carnitine on an empty stomach for optimal recovery!
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I experienced severe food poisoning after consuming rotten food, leading to vomiting and intense diarrhoea. For a week, I battled extreme nausea and high fever. My body rejected all food, even well-digested options, and I could hardly eat. After taking two tablets for diarrhoea, I gradually improved. This product effectively cleared out my intestine, which is crucial for recovery.
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I absolutely love this probiotic! Although I occasionally experience nausea and rejection of food, a single capsule quickly alleviates my discomfort. I took them while in Thailand, and they proved immensely helpful. I highly recommend them and will definitely order more.
This product stopped my lifelong battle with diarrhoea almost immediately. I increased my dosage to six pills a day, and my stools transformed from wet and unmanageable to perfectly normal within days. It even helped a friend with constipation! This product addresses the root cause of digestive issues, healing rather than masking them.
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